Thermo Fisher Scientific 5-Methylcytosine Polyclonal Antibody
상품 옵션 정보 | |||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA585516 | - | Thermo Fisher Scientific PA585516 5-Methylcytosine Polyclonal Antibody 100 ul pk | 재고문의 | pk | 673,000원 | - | 740,300원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Dot blot (DB)
Assay-dependent
Immunomicroscopy (IM)
Assay-dependent
Methylated DNA Immunoprecipitation (MeDIP)
Assay-dependent
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
The immunogen used to generate this antibody corresponds to 5-MethylCytosine/ 5-mC
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
7.55 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792656
Product Specific Information
Keep as concentrated solution.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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