Thermo Fisher Scientific UBE2C Polyclonal Antibody
UBE2C 단백질을 인식하는 Thermo Fisher Scientific의 산양 유래 폴리클로날 항체로, Western blot, ICC/IF, Flow cytometry, IP 등 다양한 응용에 적합합니다. 고순도 항체로 세포주기 및 암 연구에 활용 가능하며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QETYSKQVTSQEP) corresponding to the C-terminus amino acids of UBE2C (aa 167–179) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983925 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
The UBE2C gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is essential for the destruction of mitotic cyclins and cell cycle progression and may be involved in cancer progression. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, it catalyzes Lys-11- and Lys-48-linked polyubiquitination. UBE2C acts as an essential factor of the anaphase-promoting complex/cyclosome (APC/C), a ubiquitin ligase that regulates mitotic progression by promoting degradation of APC/C substrates through Lys-11-linked polyubiquitin chains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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