Thermo Fisher Scientific TLR11 Polyclonal Antibody
TLR11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Flow Cytometry에 최적화되어 있으며, 마우스 및 랫트 반응성. 단백질 G 정제, PBS 버퍼에 0.05% sodium azide 포함. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
- Publications: View 1 publication
Flow Cytometry (Flow)
- Tested Dilution: 0.5–1 µg/10⁶ cells
- Publications: View reference
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 911–926 (CEQLKRRLSKAGQERD) of mouse TLR11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2204418 |
Target Information
The Toll-like receptor (TLR) family in mammals comprises transmembrane proteins characterized by multiple leucine-rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. TLRs are phylogenetically conserved mediators of innate immunity essential for microbial recognition.
TLR11 specifically responds to uropathogenic bacteria rather than known TLR ligands. TLR11-deficient mice are highly susceptible to kidney infections by these bacteria, suggesting that TLR11 plays a protective role in preventing infections of internal organs in the urogenital system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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