Thermo Fisher Scientific FABP5 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human FABP5/E-FABP.

Target Information

FABP5 (fatty acid binding protein 5, psoriasis-associated) is a protein encoded by the FABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, and Epidermal-type fatty acid-binding protein.
It belongs to a family of small, highly conserved cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with a molecular weight of 15,164 Da.
This gene encodes the fatty acid-binding protein found in epidermal cells and was first identified as being upregulated in psoriasis tissue. FABPs are involved in fatty acid uptake, transport, and metabolism.
Kaczocha et al. (2009) identified FABP5 and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.