Thermo Fisher Scientific Cytokeratin 8 Polyclonal Antibody
Rabbit polyclonal antibody against human Cytokeratin 8. Validated for WB, IHC, and ICC applications. High specificity with antigen affinity purification. Supplied as a liquid form with 500 µg/mL concentration for reliable research use.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Cytokeratin 8 protein (amino acids 92–393 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903574 |
Target Information
Cytokeratin 8 is a member of the type II keratin family located on chromosome 12. Type I and type II keratins form intermediate filaments in epithelial cells. Cytokeratin 8 typically dimerizes with keratin 18 to form filaments in simple epithelial cells. It contributes to cellular structural integrity, signal transduction, and differentiation. Mutations in this gene have been associated with cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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