Thermo Fisher Scientific PROZ Monoclonal Antibody (OTI3A11), TrueMAB
Human PROZ 단백질을 인식하는 Mouse monoclonal 항체로 Western blot에 최적화됨. Lyophilized 형태이며 재구성 후 1 mg/mL 농도로 사용 가능. PBS buffer(8% trehalose)로 안정화되어 있으며, -20°C에서 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 115–400 of human PROZ produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Protein Z (PROZ) is a vitamin K-dependent plasma glycoprotein (62 kDa, 396 amino acids).
It contains four domains: a Gla-rich region, two EGF-like domains, and a trypsin-like domain.
Although structurally related to serine proteases (factors VII, IX, X, and protein C), it lacks catalytic activity.
Protein Z participates in the coagulation cascade, aiding degradation of factor Xa via protein Z-related protease inhibitor (ZPI).
Deficiency has been variably associated with thrombosis or bleeding tendencies.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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