Thermo Fisher Scientific CaV1.3 Monoclonal Antibody (S48)
CaV1.3 단백질을 인식하는 Mouse 모노클로날 항체로, WB, IHC, ICC, IP 등 다양한 실험에 사용 가능. Human, Mouse, Rat 반응성. Protein G 정제, PBS/glycerol buffer 저장. 약 250kDa 단백질 검출, Cav1.2와 비교 시 교차반응 없음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-Dependent |
| Antibody Microarray (AM) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S48 |
| Immunogen | Fusion protein amino acids 859–875 of rat Cav1.3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735140 |
Additional Formats Available
Product Specific Information
- 1 µg/mL of MA5-27716 detects Cav1.3 in 10 µg of rat brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody.
- Detects approximately 250 kDa.
- No cross-reactivity against Cav1.2.
Target Information
CACNA1D (also known as PASNA, SANDD, or Cav1.3) encodes the alpha-1D subunit of voltage-dependent calcium channels. These channels mediate calcium ion entry into excitable cells and are involved in muscle contraction, hormone or neurotransmitter release, and gene expression.
Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The alpha-1 subunit forms the pore and determines channel properties. Multiple alpha-1 isoforms (A, B, C, D, E, and S) define the characteristics of each channel type.
Several transcript variants encoding different isoforms have been identified for CACNA1D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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