Thermo Fisher Scientific CaMKII alpha/beta/delta Polyclonal Antibody
CaMKII alpha/beta/delta 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. IHC 등 다양한 응용에 적합하며, 토끼 IgG 호스트 기반. 액상 형태로 제공되며 -20°C 보관. 연구용으로 세포 신호전달 및 단백질 인산화 연구에 활용 가능.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: -
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Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
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Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: -
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Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human CaMK2 alpha/beta/sigma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2554841 |
Target Information
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases including CaMKI, CaMKII, and CaMKIV.
CaMKII is an ubiquitously expressed serine/threonine protein kinase activated by Ca²⁺ and calmodulin (CaM), implicated in regulation of the cell cycle and transcription.
There are four CaMKII isozymes—alpha, beta, gamma, and delta—which may or may not be co-expressed in the same tissue type.
CaMKII alpha is autophosphorylated on Thr286 upon binding of the Ca²⁺/CaM complex to the autoinhibitory domain, a process known as Ca²⁺/CaM trapping, thought to be involved in synaptic encoding of information.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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