Thermo Fisher Scientific Phospho-Caspase 6 (Ser257) Polyclonal Antibody
Phospho-Caspase 6 (Ser257) 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 액상 형태로 제공되며 -20°C에서 보관합니다. Caspase-6 관련 세포사멸 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257 (K-V-SP-Q-R) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554843 |
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates. They cleave after aspartic acid residues and are classified into two main groups: initiator caspases (activated by receptor clustering) and effector caspases (activated by mitochondrial permeability transition). Initiator caspases such as Caspase-8 and Caspase-9 activate effector caspases like Caspase-3 and Caspase-7, leading to cell apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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