Thermo Fisher Scientific Phospho-AP2M1 (Thr156) Polyclonal Antibody
AP2M1 단백질의 Thr156 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 액상 형태로 제공되며, 농도는 1 mg/mL입니다. 세포 내 단백질 수송 및 엔도사이토시스 연구에 유용합니다.
- 판매단위
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human AP-2mu around the phosphorylation site of Thr156 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817557 |
Target Information
The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family.
The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping during the acidification of endosomes and lysosomes.
AP2M1 has been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use the AP-2 complex to enhance endocytosis of both CD4 and class I MHC.
AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein.
At least two isoforms of AP2M1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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