Thermo Fisher Scientific LMX1A Polyclonal Antibody
LMX1A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 인간 및 다양한 종에 반응하며, 도파민 신경세포 분화 연구에 적합. 액상 형태로 제공되며 4°C 보관 가능.
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- PA124402
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human LMX1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2136838 |
Product Specific Information
- Recommended positive controls: human B lymphoblast, Jurkat
- Predicted reactivity: Cow (100%), Dog (100%), Guinea Pig (100%), Horse (86%), Mouse (93%), Rabbit (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family, which plays an essential role in pattern formation during development.
LMX1A binds an A/T-rich sequence and functions as a transcriptional activator of the insulin gene promoter in the nucleus.
During embryonic development, LMX1A is expressed along the neuraxis and contributes to roof plate formation of the vertebrae.
It is crucial for dopamine neuron differentiation, while the related LMX1B is involved in both development and survival of these cells.
LMX1A may serve as a useful biomarker or risk factor in tumor aggressiveness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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