Thermo Fisher Scientific Spastin Polyclonal Antibody
Spastin 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 적합. Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of mouse Spastin (Spastic paraplegia 4 protein) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Spastin.
Target Information
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this family share an ATPase domain and function in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis.
The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full-length sequences have not been determined.
Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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