Thermo Fisher Scientific Spastin Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Reconstitute in 100 µL of sterile water.
• Centrifuge to remove any insoluble material.
• Specificity: Spastin.

Target Information

This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this family share an ATPase domain and participate in diverse cellular processes such as membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full-length sequences have not been determined. Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.