
Thermo Fisher Scientific MLLT11 Polyclonal Antibody
MLLT11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(P)에서 검증된 항체로, 인간·마우스·랫트 시료에 반응. 고순도 정제 및 안정적 PBS/glycerol 보존 용액 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MLLT11 (Accession Q13015), corresponding to amino acid residues M1–T35 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852398 |
Product Specific Information
Antibody detects endogenous levels of total MLLT11.
Target Information
The gene variously symbolized ALL1, HRX, or MLL, located on 11q23, has been demonstrated to be fused with a number of translocation partners in cases of leukemia.
t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in two infants with acute myelomonocytic leukemia have been demonstrated.
The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23.
This gene encodes 90 amino acids and is highly expressed in the thymus but not in peripheral lymphoid tissues.
In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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