Thermo Fisher Scientific Human IgA Recombinant Rabbit Monoclonal Antibody (JM10-42)
Human IgA를 인식하는 재조합 토끼 단클론 항체로, 높은 특이성과 재현성을 제공합니다. Western blot, IHC, ICC, IP 등 다양한 응용에 적합합니다. HEK293 세포에서 발현되며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| Immunoprecipitation (IP) | 1:50–1:100 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM10-42 |
| Immunogen | Recombinant full length protein of Human IgA (aa 1–353) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809852 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened to select optimal candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
Human IgA (Immunoglobulin A) is an antibody produced by the immune system in response to antigens. It is the predominant immunoglobulin in mucosal secretions such as saliva, tears, and breast milk, playing a crucial role in defense at mucosal surfaces.
IgA binds to antigens to prevent pathogen entry, activates complement, and promotes phagocytosis by immune cells.
Human IgA is used in research to study immune responses and to develop diagnostic and therapeutic tools for infectious diseases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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