Thermo Fisher Scientific PPT1 Monoclonal Antibody (OTI1F10), TrueMAB
PPT1 단백질을 인식하는 Mouse monoclonal antibody. Western blot과 IHC(P)에서 검증됨. Human PPT1(aa 100-306) 재조합 단백질로 면역화. 동결건조 형태, PBS buffer(8% trehalose) 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 100–306 of human PPT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The PPT1 protein is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation.
It removes thioester-linked fatty acyl groups such as palmitate from cysteine residues.
Defects in this gene are associated with infantile neuronal ceroid lipofuscinosis 1 (CLN1, INCL) and neuronal ceroid lipofuscinosis 4 (CLN4).
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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