Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI3E1), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The PTPRE gene encodes a member of the protein tyrosine phosphatase (PTP) family, which are signaling molecules regulating various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants exist:

• A receptor-type PTP with a short extracellular domain, single transmembrane region, and two tandem intracytoplasmic catalytic domains.
• A nonreceptor-type isoform with a distinct hydrophilic N-terminus.

Studies in mice suggest that PTPRE plays regulatory roles in RAS-related signal transduction, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.