Thermo Fisher Scientific Phospho-TGFBR2 (Tyr259) Polyclonal Antibody
TGFBR2 인산화 부위(Tyr259)를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로 세포 증식 조절 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthesized phosphopeptide derived from human TGF beta Receptor II around the phosphorylation site of Tyr259 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transforming Growth Factor beta Receptor II (TGFBR2, also known as AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases.
It plays an essential role in the regulation of cell proliferation.
TGFBR2 encodes the gamma subunit of the catalytic core of mitochondrial ATP synthase, which catalyzes ATP synthesis using a proton gradient across the inner membrane during oxidative phosphorylation.
The catalytic portion of ATP synthase consists of five subunits (α, β, γ, δ, ε) with a stoichiometry of 3α, 3β, and one of each of the others.
The proton channel comprises three main subunits (a, b, c).
Alternatively spliced transcript variants encoding different isoforms have been identified.
A pseudogene of TGFBR2 exists on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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