Thermo Fisher Scientific SNRNP200 Polyclonal Antibody
SNRNP200 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 ICC/IF 실험에 적합합니다. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보존되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SNRNP200. Recombinant protein control fragment (Product # RP-88770) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647685 |
Product Specific Information
Immunogen sequence:
LHPRDIDAFW LQRQLSRFYD DAIVSQKKAD EVLEILKTAS DDRECENQLV LLLGFNTFDF IKVLRQHRMM ILYCTLLASA QSEAEKERIM GKMEADPELS KFLY
Antigen sequence identity:
- Mouse: 98%
- Rat: 100%
Target Information
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5, and U6, together with approximately 80 conserved proteins.
U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins and belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and catalyzes ATP-dependent unwinding of U4/U6 RNA duplexes.
Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, though the full-length nature of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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