Thermo Fisher Scientific TGFBR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 237-549 of human TGF beta Receptor II (TGFBR2) (NP_0032334) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TGFBR2,uniProtId:P37173-1,ncbiNodeId:9606,antigenRange:237-549,antigenLength:567,antigenImageFileName:PA5-88247_TGFBR2_P37173-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88247_TGFBR2_P37173-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.53 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804772

Product Specific Information

Immunogen sequence: HNTELLPIEL DTLVGKGRFA EVYKAKLKQN TSEQFETVAV KIFPYEEYAS WKTEKDIFSD INLKHENILQ FLTAEERKTE LGKQYWLITA FHAKGNLQEY LTRHVISWED LRKLGSSLAR GIAHLHSDHT PCGRPKMPIV HRDLKSSNIL VKNDLTCCLC DFGLSLRLDP TLSVDDLANS GQVGTARYMA PEVLESRMNL ENVESFKQTD VYSMALVLWE MTSRCNAVGE VKDYEPPFGS KVREHPCVES MKDNVLRDRG RPEIPSFWLN HQGIQMVCET LTECWDHDPE ARLTAQCVAE RFSELEHLDR LSG

Positive Samples: HT-29, A-549, Mouse lung; Cellular Location: Cell membrane, Single-pass type I membrane protein

Target Information

Transforming Growth Factor, beta receptor 2 (AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases. It is involved in the regulation of cell proliferation. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). TGFBR2 encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. TGFBR2 also has a pseudogene on chromosome 14.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.