Thermo Fisher Scientific Norepinephrine Transporter Monoclonal Antibody (CL3063)
인간, 마우스, 랫트에서 반응하는 노르에피네프린 수송체 단클론 항체입니다. IHC 및 IHC-P 실험에 적합하며, Protein A로 정제된 액상 형태로 제공됩니다. 1.0 mg/mL 농도, 40% 글리세롤 포함 PBS 버퍼에 저장되며 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (IHC)
Tested Dilution: -
View 3 publicationsImmunohistochemistry (Paraffin) (IHC-P)
Tested Dilution: 1:200–1:500
View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL3063 |
| Immunogen | Recombinant protein corresponding to Human Norepinephrine Transporter |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637262 |
Product Specific Information
Immunogen sequence:
SLYYLFSSFT LNLPWTDCGH TWNSPNCTDP KLLNGSVLGN HTKYSKYKFT PAAEFYERGV LHLHESSGIH DI
Binds to an epitope located within the peptide sequence HTKYSKYKFTPAAEF as determined by overlapping synthetic peptides.
Target Information
Norepinephrine Transporter (NET, or noradrenaline transporter, NAT)
Monoamine transporter responsible for the reuptake of noradrenaline from the synapse back into vesicles for storage. Also transports dopamine to a lesser degree.
Decreased NET levels have been observed in the locus coeruleus of patients with major depression.
Cocaine, amphetamines, and antidepressants such as SNRIs and TCAs increase noradrenaline by inhibiting NET.
Deficits in the NET gene have also been associated with ADHD.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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