Thermo Fisher Scientific VGAT Monoclonal Antibody (CL2793)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL2793

Immunogen

Recombinant protein corresponding to Human VGAT if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VGAT,uniProtId:Q9H598-1,ncbiNodeId:9606,antigenRange:13-103,antigenLength:525,antigenImageFileName:MA5-24643_VGAT_Q9H598-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24643_VGAT_Q9H598-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637258

Product Specific Information

Immunogen sequence: ATSVSNKSQA KMSGMFARMG FQAATDEEAV GFAHCDDLDF EHRQGLQMDI LKAEGEPCGD EGAEAPVEGD IHYQRGSGAP LPPSGSKDQV G

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.

Target Information

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.