Thermo Fisher Scientific Aquaporin 5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Aquaporin 5. Recombinant protein control fragment (Product #RP-103580). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Aquaporin 5,uniProtId:P55064-1,ncbiNodeId:9606,antigenRange:229-264,antigenLength:265,antigenImageFileName:PA5-64195_Aquaporin_5_P55064-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64195_Aquaporin_5_P55064-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.30 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638105

Product Specific Information

Immunogen sequence: SLSLSERVAI IKGTYEPDED WEEQREERKK TMELTT

Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.

Target Information

Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.