Thermo Fisher Scientific RANBP3 Recombinant Rabbit Monoclonal Antibody (B24H15L41)
RANBP3 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 높은 특이성과 일관된 로트 간 품질을 제공하며, Expi293 시스템에서 생산된 동물유래 성분 무첨가 항체입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | B24H15L41 |
| Immunogen | Recombinant protein corresponding to amino acids 151–228 of RANBP3 (UniProt ID: Q9H6Z4-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532281 |
Product Specific Information
- Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates a ~25 kDa light chain and a ~50 kDa heavy chain.
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning antibody DNA sequences from immunoreactive rabbits.
- Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Ran binding protein 3 (RanBP3) is a member of Ran GTPase binding proteins located at the nuclear pore complex (NPC). It plays an essential role in transport between cytoplasm and nucleus.
RANBP3 is expressed as two spliced forms, RanBP3a and RanBP3b, both containing two FXFG motifs characteristic of nucleoporins, a nuclear localization signal (amino acids 40–57), and an acidic carboxyl terminus integral to its switch function.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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