Thermo Fisher Scientific RANBP3 Recombinant Rabbit Monoclonal Antibody (B24H15L41)

Applications

Product Specifications

Product Specific Information

• Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates a ~25 kDa light chain and a ~50 kDa heavy chain.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning antibody DNA sequences from immunoreactive rabbits.
• Advantages include:
  • Better specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulations
  • Broader immunoreactivity due to larger rabbit immune repertoire

Target Information

Ran binding protein 3 (RanBP3) is a member of Ran GTPase binding proteins located at the nuclear pore complex (NPC). It plays an essential role in transport between cytoplasm and nucleus.
RANBP3 is expressed as two spliced forms, RanBP3a and RanBP3b, both containing two FXFG motifs characteristic of nucleoporins, a nuclear localization signal (amino acids 40–57), and an acidic carboxyl terminus integral to its switch function.

For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.