Thermo Fisher Scientific DTNA Monoclonal Antibody (OTI1B11), TrueMAB
DTNA 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, ICC/IF, Flow Cytometry에 사용 가능. Human 시료 반응성. Lyophilized 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B11 |
| Immunogen | Full length human recombinant protein of human DTNA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The DTNA gene encodes a protein belonging to the dystrobrevin subfamily of the dystrophin family.
This protein is a component of the dystrophin-associated protein complex (DPC), which includes dystrophin and several integral and peripheral membrane proteins such as dystroglycans, sarcoglycans, syntrophins, and alpha- and beta-dystrobrevin.
DPC localizes to the sarcolemma, and its disruption is linked to various muscular dystrophies.
Mutations in DTNA are associated with left ventricular noncompaction and congenital heart defects.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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