Thermo Fisher Scientific DMRT1 Monoclonal Antibody (OTI4B5), TrueMAB
DMRT1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 IHC(P) 응용에 적합합니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. 고순도 Affinity chromatography 정제, carrier-free로 재구성 및 conjugation 실험에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–210 of human DMRT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
DMRT1 gene is part of a cluster with two other family members sharing a zinc finger-like DNA-binding motif (DM domain).
The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway and a key regulator of male development in flies and nematodes.
This gene shows gonad-specific and sexually dimorphic expression. Defective testicular development and XY feminization occur when this gene is hemizygous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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