Thermo Fisher Scientific Phospho-ZO-2 (Tyr1118) Polyclonal Antibody
ZO-2 단백질의 Tyr1118 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western blot 및 IHC(Paraffin)에 적합하며, 인간·마우스·랫트 반응성. 고순도 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-ZO-2 (Tyr1118) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ZO-2 around the phosphorylation site of Tyr1118 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899315 |
Product Specific Information
Antibody detects endogenous levels of ZO-2 only when phosphorylated at Tyr1118.
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes.
CD45 is absent on non-hematopoietic cell lines and tissues.
It plays a crucial role in lymphocyte development and antigen signaling, regulating Src-family kinases and JAK kinases.
CD45 isoforms differ by alternative splicing and have distinct extracellular domains.
It is essential for T- and B-cell receptor signaling and modulates integrin-mediated signal transduction, apoptosis, and immune function regulation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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