Thermo Fisher Scientific PD-L1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0904)
PD-L1에 특이적인 alpaca 유래 재조합 단일클론 항체로 ELISA에 적합합니다. CHO 세포에서 발현되며 1 mg/mL 농도의 액상 형태입니다. Metal-chelate chromatography로 정제되었으며 PBS buffer에 보존제 없이 제공됩니다. 연구용으로만 사용 가능합니다.
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- MA554471
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Thermo Fisher Scientific PD-L1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0904)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0904 |
| Immunogen | Recombinant Human CD274 / PD-L1 / B7-H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Note: For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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