Thermo Fisher Scientific PD-L1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1177)
PD-L1을 표적으로 하는 알파카 유래 재조합 단일클론 항체로 ELISA 등 연구용에 적합. CHO 세포에서 발현되며 1 mg/mL 농도의 액상 형태. Metal-chelate chromatography로 정제되어 높은 순도 제공. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific PD-L1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1177)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1177 |
| Immunogen | Recombinant Human CD274 / PD-L1 / B7-H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Ligand binding has been shown to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant on many murine and human cancers and can be upregulated by IFN-gamma stimulation, suggesting its role in tumor immune evasion.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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