Thermo Fisher Scientific DDX10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DDX10. Recombinant protein control fragment (Product #RP-102449). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DDX10,uniProtId:Q13206-1,ncbiNodeId:9606,antigenRange:434-581,antigenLength:875,antigenImageFileName:PA5-52086_DDX10_Q13206-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52086_DDX10_Q13206-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640458

Product Specific Information

Immunogen sequence: KVPVKEIKIN PEKLIDVQKK LESILAQDQD LKERAQRCFV SYVRSVYLMK DKEVFDVSKL PIPEYALSLG LAVAPRVRFL QKMQKQPTKE LVRSQADKVI EPRAPSLTND EVEEFRAYFN EKMSILQKGG KRLEGTEHRQ DNDTGNEE

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%.

Target Information

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.