Thermo Fisher Scientific DDX10 Polyclonal Antibody
Human DDX10 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능하며 장기 보관 시 -20°C에서 보관하십시오.
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Thermo Fisher Scientific DDX10 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DDX10. Recombinant protein control fragment (Product #RP-102449). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640458 |
Product Specific Information
Immunogen sequence:
KVPVKEIKIN PEKLIDVQKK LESILAQDQD LKERAQRCFV SYVRSVYLMK DKEVFDVSKL PIPEYALSLG LAVAPRVRFL QKMQKQPTKE LVRSQADKVI EPRAPSLTND EVEEFRAYFN EKMSILQKGG KRLEGTEHRQ DNDTGNEE
Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 78%
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in various cellular processes involving RNA secondary structure alterations such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Some family members are associated with embryogenesis, spermatogenesis, and cellular growth and division.
The DDX10 gene encodes a DEAD box protein involved in ribosome assembly. Fusion of DDX10 and NUP98 by chromosome inversion 11 (p15q22) is observed in patients with de novo or therapy-related myeloid malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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