Thermo Fisher Scientific DAZAP1 Polyclonal Antibody
DAZAP1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 인간, 마우스, 랫트에서 반응합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로 안정적인 저장이 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DAZAP1. Recombinant protein control fragment (Product # RP-102467) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640386 |
Product Specific Information
Immunogen sequence:
STTQETLRSY FSQYGEVVDC VIMKDKTTNQ SRGFGFVKFK DPNCVGTVLA SRPHTLDGRN IDPKPCTPRG MQPERTRPKE GWQKGPRSDN SKSNKIFVGG IPHNCGETEL REYFKKFGVV TEVVMIYDAE KQRPR
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors. It is a ligand-activated transcription factor that binds testosterone (T) and dihydrotestosterone (DHT). Upon ligand binding, the receptor translocates into the nucleus, dimerizes, and activates transcription of androgen-responsive genes.
AR signaling is essential for development and function of male reproductive organs (prostate, epididymis) and also influences muscle, hair follicles, and brain. It regulates MAP kinase activity, and abnormalities in AR signaling are linked to diseases such as prostate cancer, Kennedy's disease, and male infertility. Mutations in this gene are associated with complete androgen insensitivity (CAIS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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