Thermo Fisher Scientific Neuropilin 1 Polyclonal Antibody
Thermo Fisher Scientific의 Neuropilin 1 Polyclonal Antibody는 인간 Neuropilin 1 단백질을 인식하는 고품질 항체로, Western blot에 적합합니다. Rabbit IgG 폴리클로날 항체이며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 606–828 of Human Neuropilin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.79 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545190 |
Product Specific Information
- Recommended positive control: HeLa
- Predicted reactivity: Mouse (95%), Rat (94%), Chicken (80%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Neuropilin 1 is a 923 amino acid membrane-bound coreceptor belonging to the neuropilin family, featuring two CUB domains, two F5/8 type C domains, and a MAM domain. It forms heterodimers with Neuropilin 2 (NRP2) and interacts with plexin (PLXNB1) to form semaphorin receptors.
Expressed primarily in the nervous system, Neuropilin 1 plays roles in cardiovascular development, angiogenesis, axon guidance, neuronal circuit formation, cell survival, neuronal migration control, and organogenesis. It functions as a receptor for semaphorins and VEGF, regulating VEGF-induced angiogenesis. Neuropilin 1 may be involved in aggressive prostate carcinoma and breast cancer progression.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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