Thermo Fisher Scientific RYK Polyclonal Antibody
RYK 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat에서 반응하며 67.5 kDa 밴드 검출. Protein A 정제, 0.4 mg/mL 농도의 액상 형태로 제공. 연구용 전용 제품.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | View publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 160–190 amino acids from human RYK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.40 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2183043 |
Product Specific Information
- Detects a band of approximately 67.5 kDa (predicted molecular weight: 72 kDa).
- Positive Control: Jurkat cell lysate.
- Store as concentrated solution. Centrifuge briefly prior to opening vial.
Target Information
RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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