Thermo Fisher Scientific SP1 Polyclonal Antibody
SP1 단백질을 검출하기 위한 Rabbit Polyclonal 항체입니다. Western blot에 최적화되어 있으며, 인간, 생쥐, 랫트 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 젤라틴 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (Internal sequence) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2194049 |
Product Specific Information
PA1-30332 detects SP1 from human, rat, and mouse samples.
Target Information
SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli.
It binds with high affinity to GC-rich motifs and regulates the expression of numerous genes involved in cell growth, apoptosis, differentiation, and immune responses.
SP1 activity is tightly regulated by post-translational modifications such as phosphorylation, sumoylation, proteolytic cleavage, glycosylation, and acetylation.
It also binds the PDGFR-alpha G-box promoter and may modulate the cellular response to DNA damage.
SP1 is implicated in chromatin remodeling and plays a role in recruiting SMARCA4/BRG1 on the c-FOS promoter, as well as regulating FE65 gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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