Thermo Fisher Scientific CD31/PECAM-1 (Endothelial Cell Marker) Monoclonal Antibody (C31.7)
CD31/PECAM-1 단클론 항체(C31.7)는 인간 및 다양한 종의 내피세포 마커로 사용되며, WB, IHC, Flow Cytometry 등에 적합합니다. 고순도 Protein A/G 정제, PBS 버퍼, 보존제 무첨가, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CD31/PECAM-1 (Endothelial Cell Marker) Monoclonal Antibody (C31.7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C31.7 |
| Immunogen | Recombinant human full-length CD31 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
- CF 488 conjugate
- PE conjugate
- Custom conjugation available upon request
Target Information
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling through immunoreceptor tyrosine-based inhibitory motifs (ITIMs). It is expressed throughout the vascular compartment, mainly at junctions between adjacent cells. The N-terminal Ig-like domain mediates homophilic binding, crucial for cell-cell interactions. CD31 plays diverse roles in integrin-mediated adhesion, transendothelial migration, angiogenesis, apoptosis, immunoregulation, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis, and thrombosis, serving as a key regulatory molecule in the vascular system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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