Thermo Fisher Scientific Cytokeratin 10 Recombinant Rabbit Monoclonal Antibody (18B6)
인간 Cytokeratin 10을 인식하는 재조합 토끼 단클론 항체로, IHC(P) 및 ELISA에 적합합니다. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 IgG 형 항체입니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- MA550147
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Cytokeratin 10 Recombinant Rabbit Monoclonal Antibody (18B6)
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 18B6 |
| Immunogen | A synthesized peptide derived from Human KRT10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092736 |
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells of both keratinizing tissues (such as skin) and non-keratinizing cells (such as mesothelial cells). Although not typical markers for endothelial cells, cytokeratins have been detected in certain microvascular endothelial cells.
There are at least 20 different cytokeratins ranging from 40–70 kDa with isoelectric points between 5–8.5, identifiable via two-dimensional gel electrophoresis.
Biochemically, CKs are categorized into two classes:
- Type I: Acidic polypeptides
- Type II: Basic polypeptides
Each epithelial cell expresses at least one member from each class. Monoclonal antibodies against cytokeratin proteins serve as valuable markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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