Thermo Fisher Scientific POLG2 Polyclonal Antibody
Human POLG2 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P)에서 1:20–1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며, 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human POLG2. Recombinant protein control fragment (Product # RP-102236) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645748 |
Product Specific Information
Immunogen sequence:
LDRGMLAYLY DSFQLTENSF TRKKNLHRKV LKLHPCLAPI KVALDVGRGP TLELRQVCQG LFNELLENGI SVWPGYLETM QSSLEQLYSK YDEMSILFTV LVTETTLENG LIHLRSRDTT MKE
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 89%
Target Information
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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