Thermo Fisher Scientific GRPEL2 Polyclonal Antibody
GRPEL2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
| Immunoprecipitation (IP) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GRPEL2. Recombinant protein control fragment (Product #RP-91013). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642224 |
Product Specific Information
Immunogen sequence:
VRSLWAGRLR VQRLLAWSAA WESKGWPLPF STATQRTAGE DCRSEDPPDE LGPPLAERAL RVKAVKLEKE VQDLTVRYQR AIADCENIRR RTQRCVEDAK IFGIQSFCKD LVE
Antigen sequence identity:
Mouse – 83%
Rat – 83%
Target Information
GRPEL2 (GrpE Like 2, Mitochondrial)
GRPEL2 is a protein-coding gene involved in mitochondrial protein import and metabolism of proteins.
Gene Ontology (GO) annotations include protein homodimerization activity and chaperone binding.
An important paralog of this gene is GRPEL1.
GRPEL2 is an essential component of the PAM complex, required for translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. It controls the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins, stimulates ATPase activity of mt-HSP70, and may modulate the interconversion between oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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