Thermo Fisher Scientific FMNL3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FMNL3. Recombinant protein control fragment (Product #RP-102029). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FMNL3,uniProtId:Q8IVF7-1,ncbiNodeId:9606,antigenRange:413-538,antigenLength:1028,antigenImageFileName:PA5-54720_FMNL3_Q8IVF7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54720_FMNL3_Q8IVF7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641683

Product Specific Information

Immunogen sequence: LDLENENMMR VAELEKQLLQ REKELESIKE TYENTSHQVH TLRRLIKEKE EAFQRRCHLE PNVRGLESVD SEALARVGPA ELSEGMPPSD LDLLAPAPPP EEVLPLPPPP APPLPPPPPP LPDKCP

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.

Target Information

FMNL3, also known as Formin-like protein 3, is a 1028 amino acid containing protein involved in immunity or defense. This developmental protein is implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway. It belongs to the formin homology family and contains a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain and has high sequence identity to the mouse Wbp3 protein. Two different isoforms have been described. Itis suspectedbe involved in gastric cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.