Thermo Fisher Scientific B4GALT1 Polyclonal Antibody
Thermo Fisher Scientific의 B4GALT1 Polyclonal Antibody는 인간 B4GALT1 단백질을 인식하는 토끼 IgG 항체입니다. Western blot 및 유세포분석에 사용 가능하며, 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 적합합니다.
- 카탈로그번호
- PA549655
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 329–358 amino acids from the C-terminal region of human B4GalT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2635108 |
Product Specific Information
Predicted to react with bovine and mouse based on sequence homology.
Target Information
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that have exclusive specificity for the donor substrate UDP-galactose and transfer galactose in a beta1,4 linkage to acceptor sugars such as GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct role in synthesizing various glycoconjugates and saccharide structures.
As type II membrane proteins, they possess an N-terminal hydrophobic signal sequence that targets the protein to the Golgi apparatus, functioning as a transmembrane anchor. Based on sequence similarity, beta4GalTs are grouped into four categories:
- beta4GalT1 and beta4GalT2
- beta4GalT3 and beta4GalT4
- beta4GalT5 and beta4GalT6
- beta4GalT7
This gene is unique among the beta4GalT family because it encodes an enzyme involved in both glycoconjugate and lactose biosynthesis. The enzyme adds galactose to N-acetylglucosamine residues in glycoproteins and forms a heterodimer with alpha-lactalbumin in lactating mammary tissue to catalyze lactose synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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