Thermo Fisher Scientific DTX4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DTX4 protein. Validated for WB, IHC, and Flow Cytometry. Purified by Protein A and antigen affinity chromatography. Suitable for research use in Notch signaling studies.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 56–83 amino acids from the N-terminal region of human DTX4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2635106 |
Product Specific Information
Predicted to react with mouse based on sequence homology.
Target Information
DTX4 is a regulator of Notch signaling, a pathway involved in cell-cell communication and regulation of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating Lys48-linked polyubiquitination and promoting degradation of TBK1. Targeting to TBK1 requires interaction with NLRP4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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