
Thermo Fisher Scientific LAMTOR2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal 항체로 Western Blot 및 IHC(Paraffin)에 사용 가능. HepG2 세포 용해물을 양성 대조군으로 권장하며, LAMTOR2 두 가지 isoform 모두 인식. ERK 신호전달 및 세포 증식 조절 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 18 amino acid peptide near the center of human LAMTOR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2554637 |
Product Specific Information
- Recommended positive control: HepG2 cell lysate
- Detects both known isoforms of LAMTOR2
- Not expected to cross-react with other LAMTOR family proteins
Target Information
The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family. Together with LAMTOR3, MAPK1, and ERK kinase 1 (MEK1), it localizes to late endosomes where it is required for efficient activation of ERK signaling. This complex regulates late endosomal trafficking, cellular proliferation, and contributes to host defense against Salmonella infection.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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