
Thermo Fisher Scientific IL36B Polyclonal Antibody
IL36B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. Western blot 및 IHC(P) 실험에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. IL-36A 및 IL-36G와 교차 반응하지 않습니다.
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Thermo Fisher Scientific IL36B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 16 amino acid peptide near the carboxy terminus of human IL-36B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2554636 |
Product Specific Information
- Recommended positive control: A549 cell lysate
- Detects only the longer isoform of IL-36B
- No cross-reactivity with IL-36A or IL-36G
- Avoid exposure to prolonged high temperatures
Target Information
IL-36B is a member of the interleukin 1 cytokine family, located within a cytokine gene cluster on chromosome 2.
It activates the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP.
Similar to IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, though the cleavage mechanism remains unknown.
IL-36 cytokines are suggested to amplify Th1 responses by enhancing proliferation and polarization of naive CD4+ T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-38032_IL36B_Q9NZH7-1_Rabbit.svg, PA5-38032_IL36B_Q9NZH7-1_Rabbit_PDP.jpeg)
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