Thermo Fisher Scientific Phospho-STAT2 (Thr387) Polyclonal Antibody
Phospho-STAT2 (Thr387) 항체로, 인간 및 생쥐 시료에서 인산화된 STAT2 단백질을 특이적으로 검출합니다. Western blot, IHC, ICC에 적합하며, 고순도의 Rabbit Polyclonal 형식으로 PBS/glycerol 용액에 보관됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STAT2 around the phosphorylation site of Thr387 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899283 |
Product Specific Information
This antibody detects endogenous levels of STAT2 only when phosphorylated at Thr387.
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases, then form homo- or heterodimers that translocate to the nucleus, acting as transcription activators. In response to interferon (IFN), STAT2 forms a complex with STAT1 and ISGF3G (p48), functioning as a transactivator but lacking direct DNA-binding ability. It also interacts with transcription adaptor P300/CBP (EP300/CREBBP), and may play a role in blocking IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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