Thermo Fisher Scientific CALHM1 Polyclonal Antibody
인간 CALHM1 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태입니다. 알츠하이머병 관련 연구 및 칼슘 항상성 조절 기전 연구에 활용 가능합니다.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P))
Recommended Dilution
- 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CALHM1. Recombinant protein control fragment (Product # RP-91132) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639235 |
Product Specific Information
Immunogen sequence:
CTEHAKAFAK VCIQQFFEAM NHDLELGHTH GTLATAPASA AAPTTPDGAE EEREKLRGIT DQGTMNRLLT SWHKCKPPLR LGQEEPPLMG NGW
Sequence identity:
- Mouse: 82%
- Rat: 80%
Target Information
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by neuronal loss and senile plaques composed of aggregated amyloid-beta (Aβ) peptides derived from amyloid precursor protein (APP).
CALHM1 (Calcium Homeostasis Modulator 1) is a multipass transmembrane glycoprotein that regulates cytosolic Ca²⁺ concentration and Aβ levels.
It has been implicated in Alzheimer’s disease susceptibility and modulates Ca²⁺-dependent proteolytic processing of APP.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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