Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI8E5), TrueMAB
RAD23B 단백질을 인식하는 Mouse Monoclonal Antibody (OTI8E5). Western Blot에 최적화되어 있으며, 인간 단백질에 반응합니다. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol buffer로 안정화. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA804897
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–253 of human RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The RAD23B protein is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). It complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts in vitro. RAD23B interacts with and enhances the activity of 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition in base excision repair. The N-terminal ubiquitin-like domain interacts with the 26S proteasome, indicating involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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