Thermo Fisher Scientific FGG Monoclonal Antibody (OTI1F5), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
To use this carrier-free antibody for conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains.
Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the primary component of blood clots.
Cleavage products of fibrinogen and fibrin regulate cell adhesion, spreading, vasoconstriction, chemotaxis, and act as mitogens for various cell types.
Mutations in this gene can cause disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia.
Alternative splicing results in two transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.