Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI1G4), TrueMAB
인간 ICAM3 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 동결건조 형태로 공급되며, PBS(8% 트레할로스) 버퍼에 보존됩니다. 면역세포 간 상호작용 연구 및 ICAM3 관련 신호전달 연구에 유용합니다.
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Applications
- Western Blot (WB): 1:400–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G4 |
| Immunogen | Full length human recombinant ICAM3 protein produced in HEK293T cells. Target family: CD50 (ICAM3), UniProt ID: P32942-1, Antigen range: 1–547 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD50 (ICAM-3) is a transmembrane glycoprotein expressed by leukocytes and acts as a counter-receptor for LFA-1 integrin. It mediates adhesion between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and promotes T cell activation and proliferation.
ICAM-3 is crucial in initiating immune responses and interacts with CD209 (DC-SIGN) on dendritic cells and macrophages, facilitating communication between dendritic cells and granulocytes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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