Thermo Fisher Scientific Pembrolizumab Recombinant Rabbit Monoclonal Antibody (94B9), MonoRab
사람 PD-1 단백질을 인식하는 재조합 토끼 단클론 항체로, Pembrolizumab을 면역원으로 제작되었습니다. ELISA 및 Blocking Assay에 적합하며, 단백질 A로 정제된 동결건조 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA (ELISA) | 0.01–0.1 µg/mL |
| Blocking Assay (BLOCK) | 10–50 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Mammalian cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 94B9 |
| Immunogen | Pembrolizumab |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Pembrolizumab (Keytruda) is a humanized monoclonal antibody approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in activation of T-cell-mediated immune responses against tumor cells.
GenScript MonoRab™ Anti-Pembrolizumab Antibody (94B9), mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Pembrolizumab.
Target Information
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that binds to PD-1 and inhibits its interaction with PD-L1, leading to T-cell activation against tumor cells. It is approved for the treatment of unresectable or metastatic melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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