Thermo Fisher Scientific Daratumumab Recombinant Rabbit Monoclonal Antibody (139B10), MonoRab

Applications

Tested Dilution

Publications

ELISA (ELISA)

0.01-0.1 µg/mL

-

Blocking Assay (BLOCK)

1-10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

Mammalian cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

139B10

Immunogen

Daratumumab

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.02% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.

Daratumumab (Darzalex) is a human IgG1k monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of multiple myeloma. It binds with high affinity to CD38, which is highly expressed on the surface of multiple myeloma cells. Daratumumab can make immune system to attack cancer cells, resulting in rapid tumor cell death through immunomodulatory effects.GenScript MonoRab™ Anti-Daratumumab Antibody (139B10), mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Daratumumab.

Target Information

Daratumumab (Darzalex) is a human monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of multiple myeloma. Daratumumab binds to CD38 on multiple myeloma cells and induces cells to apoptose via antibody-dependent cellular cytotoxicity or complement-dependent cytotoxicity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.